Neuroscience JUST Did the IMPOSSIBLE: Psilocybin Rewires the Brain (and What It Means for YOU)

This neuroscience paper published in Cell reveals how psilocybin alters brain connectivity during a psychedelic experience. Using a genetically modified rabies virus as a neural tracer, researchers mapped how psilocybin affects brain regions, explaining why it can reduce depression and anxiety, quiet the default mode network, intensify sensory perception, and lead to lasting psychological change. The study highlights that only active brain regions undergo lasting rewiring, with significant implications for mental health treatment and psychotherapy.